TB/HIV

         

HIV epidemic has posed major challenges to TB control efforts globally. HIV weakens the immune system.  Someone who is HIV-positive and infected with TB is 5-7 times more likely to develop active TB than someone infected with TB but not infected with HIV.  TB is a leading cause of death among people who are HIV-positive accounting for about 11% of AIDS deaths worldwide. 

 

Countries in the South-East Asia Region are beginning to witness increasing numbers of TB-HIV co-infected individuals. The “dual strategy for a dual epidemic” approach needs to be replaced by a comprehensive and coherent response through a health strategy that addresses both TB and HIV.  The extent of the TB/HIV epidemic in the Region will depend on the future course of the HIV epidemic, as well as on efforts to control TB.  It will require full implementation of DOTS.  It includes preventing HIV infection, preventing progression of latent TB infection to active disease and the provision of HIV/AIDS care and antiretroviral treatment on a long-term basis.  Tuberculosis is the most common opportunistic disease in Asia among people living with HIV/AIDS.  While the double stigma of HIV and TB leads to delays in TB diagnosis and treatment, mortality in HIV+ TB patients is also higher due to a worse prognosis or other opportunistic infections occurring.  With scaling-up antiretroviral therapy in South-East Asia, management of TB/HIV will need special attention in both programmes.

 

*     Some facts about TB/HIV

 

*     TB is an opportunistic disease that preys on weakened immune systems; if not diagnosed early it can move very quickly in HIV-positive individuals. 

*     TB is the leading infectious killer of people living with HIV/AIDS. 

*     Up to 50% of people with HIV or AIDS develop TB. 

*     Worldwide, 14 million are co-infected with TB and HIV.  In the SEA Region approximately three million are co-infected.

*     TB causes at least 11% of AIDS deaths and possibly as many as 50%. 

*     The lifetime risk of developing TB in an HIV-positive individual is 50% as compared to the 5-10% risk of someone who is HIV-negative

*     Most importantly, TB can successfully be treated even if someone is HIV-infected.

*     Treatment of TB can prolong and improve the quality of life for HIV-positive people but cannot alone prevent people from dying of AIDS.

*     In the South East Asia Region five of the 11 countries are high- or moderate-TB/HIV burden countries: India, Indonesia, Myanmar, Nepal and Thailand.

 

*     Activities on TB/HIV in the South-East Asia Region

 

That the incidence of both diseases is the highest in the economically productive age groups, poses significant threats not only to health; but also to social and economic development in the Region.  WHO SEARO has taken the following initiatives in response to this dual epidemic in the Region:

 

*     Regional Level

 

*     Joint meetings of NTP and NAP managers 2001 and 2002

*     NTP managers briefed on 3 by 5 at NTP Managers’ meeting 2003

*     Participation in the Global TB/HIV Working Group

*     HIV/TB Regional framework developed and disseminated

*     SEARO supported pilot projects at district level; assessment of on-going interventions in countries; support for plans to scale up

*     TB/HIV Conference for the Mekong Region countries(2004)

*     Regional training course on TB-HIV planned January 2005

 

*     Country level

 

*     Thailand:

 

*     Structural integration; nation-wide HIV-TB interventions, including INH preventive therapy at 22 sites

 

*     India, Indonesia, Myanmar and Nepal:

 

*     Central level working groups/task forces on HIV-TB; national policy formulated

*     HIV-TB surveillance at selected sentinel sites; (India, Indonesia, Myanmar)

*     Guidelines and training materials developed; TB-HIV interventions initiated at selected sites (India, Myanmar); GFATM support sought for scaling up

 

*     Trainings

 

WHO is organizing, in collaboration with the Ministry of Public Health, Thailand; the US Centres for Disease Control and Prevention (CDC), Atlanta; and the Research Institute for Tuberculosis (RIT), Tokyo, the first training course on TB/HIV for national and peripheral level TB and AIDS programme personnel from five countries (India, Indonesia, Myanmar, Nepal and Thailand) in the South East Asia Region. This training course is scheduled to take place from 17-28 January 2005 in Bangkok, Thailand, with field visits to pilot TB/HIV projects in Ubon Ratchatanee and Chiang Rai.

 

*     Publications (The PDF version of publications is available under ‘Browse all Publication’ link available on this page)

 

*     SEARO: Regional Strategic Plan on HIV/TB (PDF Version)

*     List of TB/HIV documents from WHO

                                                                          

     

 

*     Links

 

*      WHO FAQs about TB/HIV:
http://www.who.int/tb/hiv/faq/en/

*      Stop TB Partnership coverage of XV International AIDS Conference: http://www.stoptb.org/events/internationalaidsconference/xv/

*      Information pack and advocacy materials on TB/HIV: http://www.stoptb.org/events/internationalaidsconference/xv/TBHIVInformationPack.asp

 

 

||| | ||